The Group

Along with a pool of associates, PHF SA forms part of Nine Trees Group S.p.A., a large Italian group that operates in the production of active and
intermediate ingredients for the global pharmaceutical industry.

F.I.S. – Fabbrica Italiana Sintetici S.p.A.

Fabbrica Italiana Sintetici S.p.A. (Italy) specialises in the production in the production of chemical products for the pharmaceutical industry, especially in Custom Synthesis, i.e. the exclusive production of intermediate, advanced intermediate and active ingredients for patent holding pharmaceutical companies and, as such, pharmaceutical specialities. F.I.S. also has a presence in the generic market in which it develops and sells active ingredients such as tranquillisers, anxiolytics, anti-bacterial agents, anticonvulsants, anti-inflammatory drugs, diuretics, analgesics and cardiovascular drugs. The F.I.S. Group has three sites: the main site is in Montecchio Maggiore (Veneto), where research, development and production work on Custom and Generic products is carried out; the second is in Termoli (Molise) which, although initially was involved in the production of intermediate ingredients, now also processes active and FDA approved ingredients and the third in Almisano di Lonigo (Veneto), working on development and production of generic and custom APIs.

Montecchio Maggiore (VI), Termoli (CB) and Almisano di Lonigo (VI) – ITALY


DELMAR (Canada), acquired by Holding F.I.S. in 2012, is a strategic site for the American market and is involved in the production of intermediate and active pharmaceutical ingredients.

La Salle, Quebec – CANADA


ANEMOCYTE (Italy), is a Biotech Manufacturing Organisation (BMO) active in the field of Cell and Gene Therapies (CGTs). The Company addresses CGT’s Industry needs pro-actively offering one stop shop solutions and fostering exciting innovation in all steps of product development and manufacturing.
Company’s experience and know -how come from far:
- more than a decade of GMP manufacturing of CGTs and biological drugs;
- a tradition in Contract Manufacturing of Active Pharmaceutical Ingredients (Holding F.I.S. Group) that dates back to the 50s of the last century.
Anemocyte in a nutshell:
- Process development and GMP capabilities (Somatic Cells, Non-Viral Modified Cells) and High-Quality Plasmid for Viral Vector Manufacturing;
- Project 2020: to address up to commercial scale needs (Including manufacturing and use of Viral Vectors for CGTs);
- Final Filling, finishing and lyophilization of small clinical lots (Phase I-III);
- Big Data Analysis in the field of CGTs.

Gerenzano (VA) – ITALY


ALYON INC (USA), formerly Lugano Laboratories LLC, was founded in November 2014. Wholly-owned subsidiary of PHF, Alyon is dedicated to commercial operations and to the development of PHF's market in the USA.

Hackensack, New Jersey – USA