ADSORBED NANOEMULSION SYSTEM (ANeS)PCT IB2011/001017
THE MAJOR CHALLENGE IN DEVELOPING A PRODUCT:
ACTIVE INGREDIENTS SOLUBILITY
Most of vegetal or synthetic small molecules are characterized by a high hydrophobicity, which causes poor affinity for biological membranes and insufficient bioavailability. When molecules are not able to solubilize, they are not absorbed by the systemic circulation and do not exert their activity.
OUR SOLUTION IS
A PATENTED TECHNOLOGICAL SYSTEM, DERIVED FROM NeDS PATENT, CONSTITUTED BY A PARTICULAR POOL OF EXCIPIENTS THAT HAS BEEN STUDIED TO:
THE TECHNOLOGY BEHIND ANeS
ANeS is a solid powder made by a liquid core in which the active ingredients are solubilized or suspended. The peculiar granulation process of the solid matrix produces a powder that has excellent technological performances (smoothness, machinability).
ORO-SOLUBLE OR WATER-SOLUBLE POWDERS
THIS PHARMACEUTICAL FORM ALLOWS TO:
Deliver great quantities of active ingredients (which is not possible with NeDS)
Mask the unpleasant taste of some ingredients
DATA ON RESVERATROL EFFICACY IN A SPECIFIC FORMULATION FOR THE TREATMENT OF HOT FLUSHES
THE ADMINISTRATION OF RESVERATROL THROUGH ANES TO 108 MENOPAUSAL WOMEN HAS REDUCED BOTH THE NUMBER (PRIMARY OUTCOME) AND THE INTENSITY (SECONDARY OUTCOME) OF HOT FLUSHES.