Tecnologie

 

ADSORBED NANOEMULSION SYSTEM (ANeS)

 PCT IB2011/001017

THE MAJOR CHALLENGE IN DEVELOPING A PRODUCT:
ACTIVE INGREDIENTS SOLUBILITY

Most of vegetal or synthetic small molecules are characterized by a high hydrophobicity, which causes poor affinity for biological membranes and insufficient bioavailability. When molecules are not able to solubilize, they are not absorbed by the systemic circulation and do not exert their activity.

OUR SOLUTION IS

A PATENTED TECHNOLOGICAL SYSTEM, DERIVED FROM NeDS PATENT, CONSTITUTED BY A PARTICULAR POOL OF EXCIPIENTS THAT HAS BEEN STUDIED TO:

DELIVER LIPOPHILIC ACTIVE INGREDIENTS

DELIVER HIGHER DOSAGES OF ACTIVE INGREDIENTS THAN NeDS

IMPROVE THEIR ABSORPTION

IMPROVE THE PALATALABILITY OF SOME ACTIVE INGREDIENTS

THE TECHNOLOGY BEHIND ANeS

ANeS is a solid powder made by a liquid core in which the active ingredients are solubilized or suspended. The peculiar granulation process of the solid matrix produces a powder that has excellent technological performances (smoothness, machinability).

TURMERIC

Q10

PHARMACEUTICAL FORM

ORO-SOLUBLE OR WATER-SOLUBLE POWDERS

 

THIS PHARMACEUTICAL FORM ALLOWS TO:


Deliver great quantities of active ingredients (which is not possible with NeDS)

Mask the unpleasant taste of some ingredients

CLINICAL DATA

DATA ON RESVERATROL EFFICACY IN A SPECIFIC FORMULATION FOR THE TREATMENT OF HOT FLUSHES

CONCLUSIONS

THE ADMINISTRATION OF RESVERATROL THROUGH ANES TO 108 MENOPAUSAL WOMEN HAS REDUCED BOTH THE NUMBER (PRIMARY OUTCOME) AND THE INTENSITY (SECONDARY OUTCOME) OF HOT FLUSHES.

MAIN ADVANTAGES

DELIVERY OF LIPOPHILIC ACTIVE INGREDIENTS

HIGH BIOAVAILABILITY

POSSIBILITY TO DELIVER GREAT QUANTITIES OF ACTIVE INGREDIENTS

TASTE-MASKING OF SOME ACTIVE INGREDIENTS